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Is there a reported connection between Lipitor and limited joint flexibility? Lipitor (atorvastatin) belongs to the class of statins, which can cause muscle and joint symptoms in some patients. These complaints range from mild soreness to rare but serious conditions such as rhabdomyolysis. Limited joint flexibility specifically is not listed as a frequent side effect, but muscle weakness and pain can indirectly affect range of motion. Why do patients report joint-related complaints on statins? Patients taking statins frequently mention muscle aches, stiffness, and occasional joint discomfort. The mechanism is not fully understood. Statins may interfere with CoQ10 production, which is needed for muscle energy production, and may also affect calcium channels in muscle cells. Some patients describe a stiffness that feels like joint limitation, but clinical trials often classify these als
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