Lipitor is a medication used to lower cholesterol levels in the blood. Grapefruit and grapefruit juice can interact with some medications, including Lipitor, and increase the risk of side effects. According to [2], the chemicals in grapefruit can block the enzymes that break down Lipitor in the body, leading to higher levels of the drug in the bloodstream. This can increase the risk of side effects such as muscle pain and liver damage. It is recommended to avoid grapefruit and grapefruit juice while taking Lipitor to reduce the risk of these side effects. [3] advises that the interaction between Lipitor and grapefruit can last for up to 72 hours, so it is best to avoid consuming grapefruit or grapefruit juice for at least three days before and after taking Lipitor. However, it is important to note that this interaction is not unique to Lipitor and can occur with other statin medications as well. Therefore, it is recommended to consult with a healthcare provider before consuming grapefruit or grapefruit juice while taking any medication.

Sources:
[2] https://www.verywellhealth.com/can-i-take-lipitor-or-zocor-with-grapefruit-juice-1124045
[3] https://ro.co/health-guide/lipitor-and-grapefruit/