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What other pain relievers work like aspirin Aspirin belongs to the group of drugs called NSAIDs. These medications relieve pain, reduce inflammation, and lower fever by blocking cyclooxygenase enzymes that produce pain and inflammation signals. Other NSAIDs provide similar relief through the same mechanism. Ibuprofen and naproxen are common alternatives. They treat headaches, muscle aches, arthritis, and menstrual cramps. They take effect quickly and usually cover 4 to 12 hours depending on the product. How do NSAIDs differ from acetaminophen Acetaminophen relieves pain and fever but does not fight inflammation. It acts mainly in the brain to raise pain thresholds and reduce fever. People who cannot take NSAIDs because of stomach, kidney, or blood issues often turn to it. Can topical pain relievers replace oral ones Topical NSAIDs such as diclofenac gel or patches deliver medicine directly to the area. They cause less stomach irritation and less whole-body exposure. They work well for localized muscle or joint pain and sometimes serve as a first choice when swelling is confined to one place. When does aspirin patent protection end Aspirin is a very old drug. Its original patents expired generations ago. No single company holds broad exclusive rights today. Generics dominate the market, so price stays low and availability remains high. Who manufactures aspirin alternatives Major manufacturers of ibuprofen and acetaminophen include Johnson & Johnson for Tylenol products, Reckitt for Nurofen, and many generic houses. Every major pharmacy chain sells its own private-label versions. What risks do these pain relievers carry NSAIDs raise risk of stomach bleeding, kidney strain, and cardiovascular events, especially at higher doses or when used long term. Acetaminophen can damage the liver if the daily limit is exceeded.
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