Can You Take Kesimpta at Home?
Yes, Kesimpta (ofatumumab) is FDA-approved for at-home self-administration by patients or caregivers after proper training from a healthcare provider. It's given as a subcutaneous injection using a prefilled Sensoready pen, typically once every 4 weeks after initial doses.[1]
How Do You Administer Kesimpta at Home?
Start with two initiation doses one week apart, supervised by a healthcare professional. From week 5 onward, inject 20 mg subcutaneously in the abdomen, thigh, or upper arm. Rotate sites to avoid irritation. Store the pen in the refrigerator; let it warm to room temperature for 15-30 minutes before use. Full instructions come with the pen and patient brochure.[1]
Who Can Self-Inject and What Training Is Required?
Adults with relapsing forms of multiple sclerosis (RMS) can self-inject or have a caregiver do it after training. Your doctor or nurse demonstrates the process, ensures you understand storage, injection technique, and what to do if issues arise. Do not self-inject without this training.[1]
What If You Miss a Dose or Have Side Effects?
Inject as soon as possible if you miss a dose, then resume your schedule. Common injection-site reactions include pain, swelling, or redness, which usually resolve quickly. Report severe reactions like infection signs or allergic responses to your doctor immediately. Always dispose of used pens in a sharps container.[1]
How Does Kesimpta Compare to Other MS Self-Injections?
Unlike infused MS drugs (e.g., Ocrevus, given in-clinic every 6 months), Kesimpta offers monthly at-home convenience. It targets B cells similarly but with a different antibody format, potentially suiting patients preferring less frequent clinic visits.[1]
[1]: Kesimpta Prescribing Information (Novartis)