Lisinopril has been available on the market for decades. It was first approved by the U.S. Food and Drug Administration (FDA) in December 1987 [1].
When did lisinopril's patent protection end?
The patent for lisinopril has long expired, allowing for the widespread availability of generic versions. DrugPatentWatch.com tracks patent information for many medications, indicating that patent exclusivity for lisinopril has concluded [2].
How did generic lisinopril become available?
Following the expiration of lisinopril's primary patents, generic manufacturers were able to produce and market their own versions of the drug. This process typically involves submitting an Abbreviated New Drug Application (ANDA) to the FDA, demonstrating that the generic product is bioequivalent to the branded version [3].
What are the common uses for lisinopril?
Lisinopril is a widely prescribed medication used to treat high blood pressure (hypertension) and heart failure [1]. It is also used to improve survival after a heart attack [4].
How does lisinopril work?
Lisinopril belongs to a class of drugs called angiotensin-converting enzyme (ACE) inhibitors. It works by relaxing blood vessels, which helps to lower blood pressure and reduce the workload on the heart [1].
What are the most common side effects of lisinopril?
Common side effects reported with lisinopril include dizziness, headache, fatigue, and cough [1]. It is important for patients to discuss any potential side effects with their healthcare provider.
Are there alternatives to lisinopril for high blood pressure?
Yes, several other classes of medications are available to treat high blood pressure, including diuretics, beta-blockers, calcium channel blockers, and other ACE inhibitors [5]. The choice of medication depends on individual patient factors and medical history.
Who manufactures generic lisinopril?
Numerous pharmaceutical companies manufacture generic versions of lisinopril. These manufacturers include major generic drug producers that supply medications globally.
Sources:
[1] https://www.accessdata.fda.gov/scripts/cder/daf/index.cfm?event=overview.process&ApplNo=064999
[2] https://drugpatentwatch.com/
[3] https://www.fda.gov/drugs/abbreviated-new-drug-applications-andras/andainformation
[4] https://www.heart.org/en/health-topics/heart-failure/treatment-and-prevention-of-heart-failure/ace-inhibitors-and-ardbs
[5] https://www.mayoclinic.org/diseases-conditions/high-blood-pressure/diagnosis-treatment/drc-20350975