See the DrugPatentWatch profile for sevelamer
Sevelamer carbonate oral suspension is manufactured by multiple companies. Among them are:
Who Else Makes Sevelamer Carbonate Oral Suspension?
Besides the originator, other manufacturers include:
* Teva Pharmaceuticals [1]
* Hikma Pharmaceuticals [2]
* Viatris [3]
* Ascend Laboratories [4]
* Pragmatic [5]
* Aurobindo Pharma [6]
* Lupin Pharmaceuticals [7]
* Sun Pharma [8]
* Amneal Pharmaceuticals [9]
These companies produce generic versions of sevelamer carbonate oral suspension, offering alternatives to the brand-name product.
When Did Sevelamer Carbonate Go Off-Patent?
The patent exclusivity for sevelamer carbonate has expired, allowing for the production of generic versions. While specific patent expiration dates can vary by region and formulation, the market has seen the introduction of multiple generics, indicating that key patents are no longer in effect [10].
How Does Sevelamer Carbonate Work?
Sevelamer carbonate is a phosphate binder. It works by binding to phosphate in the gastrointestinal tract, preventing its absorption into the bloodstream. This is crucial for patients with chronic kidney disease (CKD) on dialysis who cannot excrete excess phosphate effectively, leading to hyperphosphatemia [11].
What Are The Alternatives to Sevelamer Carbonate?
Beyond generic sevelamer carbonate, other phosphate binders are available. These include calcium-based binders (e.g., calcium acetate, calcium carbonate) and other non-calcium, non-sevelamer binders like lanthanum carbonate and ferric citrate [11]. Each has its own efficacy, side effect profile, and dosing considerations.
What Side Effects Are Associated with Sevelamer Carbonate?
Common side effects of sevelamer carbonate include gastrointestinal issues such as nausea, vomiting, diarrhea, constipation, and abdominal pain. Less common side effects can involve hypercalcemia, particularly when used concurrently with calcium supplements [11].
How Much Does Sevelamer Carbonate Oral Suspension Cost?
The cost of sevelamer carbonate oral suspension can vary significantly depending on the manufacturer, dosage, quantity, and insurance coverage. Generic formulations are generally less expensive than brand-name medications. Prices can range from approximately $50 to over $200 for a typical supply, with significant discounts available through various pharmacies and discount programs [12][13].
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1. "Sevelamer Carbonate Oral Suspension." Teva Pharmaceuticals USA, Inc.
2. "Sevelamer Carbonate Oral Suspension." Hikma Pharmaceuticals USA Inc.
3. "Viatris Announces Launch of Sevelamer Carbonate Oral Suspension." Viatris Inc.
4. "Ascend Laboratories Launches Generic Sevelamer Carbonate Oral Suspension." Ascend Laboratories, LLC.
5. "Sevelamer Carbonate Oral Suspension." Pragmatic.
6. "Aurobindo Pharma Announces Launch of Sevelamer Carbonate Oral Suspension." Aurobindo Pharma.
7. "Lupin Receives ANDA Approval for Sevelamer Carbonate Oral Suspension." Lupin Pharmaceuticals.
8. "Sun Pharma Announces Launch of Sevelamer Carbonate Oral Suspension." Sun Pharmaceutical Industries Ltd.
9. "Amneal Pharmaceuticals Launches Generic Sevelamer Carbonate Oral Suspension." Amneal Pharmaceuticals Inc.
10. DrugPatentWatch.com.
11. "Sevelamer Carbonate." National Institutes of Health: National Library of Medicine.
12. "Sevelamer Carbonate Oral Suspension Prices, Coupons & Patient Assistance Programs." Drugs.com.
13. "Sevelamer Carbonate Oral Suspension." GoodRx.