Lipitor, also known as atorvastatin, is a medication used to treat high cholesterol levels. Red yeast rice is a dietary supplement that contains monacolin K, a compound similar to atorvastatin. Both Lipitor and red yeast rice can lower cholesterol levels, but taking them together may increase the risk of side effects.

The use of red yeast rice with Lipitor can increase the risk of muscle-related side effects, such as muscle pain, weakness, and kidney damage, due to the additive effect of the two substances on inhibiting the production of cholesterol in the body [1]. The FDA has issued a warning about red yeast rice products, stating that they may contain unlabeled and varying amounts of lovastatin, a medication similar to atorvastatin [2].

Additionally, red yeast rice may interact with other medications, such as grapefruit juice, cyclosporine, and gemfibrozil, increasing the risk of side effects [3]. It is important to consult a healthcare provider before taking red yeast rice with Lipitor or any other medication.

In conclusion, taking Lipitor and red yeast rice together may increase the risk of muscle-related side effects. It is crucial to consult a healthcare provider before combining these substances.

Sources:

1. <https://www.drugs.com/drug-interactions/atorvastatin-with-red-yeast-rice-138-139-1339-1340.html>
2. <https://www.fda.gov/consumers/consumer-updates/red-yeast-rice-can-contain-unapproved-drug>
3. <https://www.mayoclinic.org/drugs-supplements-red-yeast-rice/art-20363080>
4. <https://www.drugpatentwatch.com/drugs/lipitor>