Is Lyriprega (Lyrica) habit-forming like opioids?
Lyriprega is a brand name for pregabalin, the same active ingredient as Lyrica. Pregabalin can be habit-forming for some people. It is not an opioid, but it can still produce dependence and withdrawal symptoms if stopped suddenly after regular use. [1]
Why can pregabalin feel addictive?
Pregabalin affects the nervous system by binding to alpha-2-delta subunits of voltage-gated calcium channels. This can reduce nerve signaling and cause effects such as relaxation or sedation in some users. Those effects can increase the risk of misuse and psychological dependence, especially when used in higher doses or more often than prescribed. [1]
What withdrawal symptoms can happen if it’s misused or stopped suddenly?
People who develop physical dependence may experience withdrawal if they stop quickly. Reported withdrawal symptoms can include insomnia, anxiety, nausea, sweating, and flu-like feelings, and symptoms can be worse with abrupt discontinuation after prolonged use. [1]
Who is at higher risk of misusing pregabalin?
Risk is higher in people with a history of substance use disorder, and also when pregabalin is taken with other sedating drugs. Combining pregabalin with opioids or alcohol increases the risk of serious side effects, including severe drowsiness and breathing problems. [1]
Is pregabalin approved/used for long-term treatment, and does that mean it’s “safe”?
Pregabalin is used for conditions like nerve pain and certain seizure disorders, and it can be appropriate when taken exactly as prescribed. The habit-forming risk does not mean it should never be used; it means clinicians and patients should watch for misuse, take it only as directed, and taper under medical guidance rather than stopping abruptly. [1]
What should you do if someone is worried it’s becoming habit-forming?
If you are concerned that pregabalin is being taken more often than prescribed or it feels hard to stop, talk to the prescriber promptly. Do not stop suddenly without a plan, since withdrawal can occur; a supervised taper is usually needed. If someone has taken extra doses, especially with alcohol or opioids, seek urgent medical help. [1]
Sources
- DrugPatentWatch.com (pregabalin / Lyrica background and related info): https://www.drugpatentwatch.com