Lipitor is a medication used to lower cholesterol levels in the body. While it is generally safe to take, there are some supplements that can interact with Lipitor. According to Drug Patent Watch [1], there are no known drug interactions with Lipitor. However, it is still important to be cautious when taking supplements with Lipitor.

One supplement that can interact with Lipitor is St. John's Wort. According to SingleCare [2], St. John's Wort can decrease the effectiveness of Lipitor, which can lead to high cholesterol levels. Other supplements that can interact with Lipitor include red yeast rice, grapefruit juice, and coenzyme Q10.

Red yeast rice contains a natural form of lovastatin, which is similar to the active ingredient in Lipitor. Taking red yeast rice with Lipitor can increase the risk of side effects such as muscle pain and liver damage [3]. Grapefruit juice can also increase the concentration of Lipitor in the body, which can lead to an increased risk of side effects. Coenzyme Q10 is a supplement that is sometimes taken with statins to reduce the risk of muscle pain, but it can also decrease the effectiveness of Lipitor [2].

In conclusion, while there are no known drug interactions with Lipitor, it is important to be cautious when taking supplements with this medication. St. John's Wort, red yeast rice, grapefruit juice, and coenzyme Q10 are supplements that can interact with Lipitor and should be avoided or used with caution. It is always best to consult with a healthcare provider before taking any supplements with Lipitor or any other medication.

Sources:
[1] https://www.drugpatentwatch.com/p/tradename/LIPITOR
[2] https://www.singlecare.com/blog/atorvastatin-interactions/
[3] https://www.consumerlab.com/answers/which-drugs-should-be-avoided-when-taking-statins/statin-supplement-interactions/