Lokelma is a medication prescribed for the treatment of hyperkalemia, a condition characterized by elevated potassium levels in the blood. It is available in a sachet form [1].
How does Lokelma work to lower potassium?
Lokelma works by binding to potassium in the gastrointestinal tract. This binding prevents potassium from being absorbed into the bloodstream, and the bound potassium is then eliminated from the body through feces [1]. The active ingredient in Lokelma is sodium zirconium cyclosilicate [2].
How is Lokelma administered?
Lokelma is taken orally as a powder from a sachet. The powder can be mixed with water or other liquids before consumption [1].
Who manufactures Lokelma?
Lokelma is developed and marketed by AstraZeneca [3].
What are the potential side effects of Lokelma?
Common side effects associated with Lokelma include diarrhea, constipation, and nausea [1]. Patients should consult with their healthcare provider regarding any potential side effects [1].
What is the pricing and availability of Lokelma?
Pricing and availability can vary based on location and insurance coverage. Information on obtaining Lokelma can be discussed with a healthcare professional or pharmacist [1].
Are there any drugs similar to Lokelma?
Patiromer is another medication used to treat hyperkalemia by binding to potassium in the gastrointestinal tract [4].
When does the patent for Lokelma expire?
Patent information for specific drugs like Lokelma can be found on resources such as DrugPatentWatch.com [5]. The expiration of patents can influence the availability of generic alternatives.
Sources
1. Lokelma (sodium zirconium cyclosilicate) sachets. National Health Service.
2. Sodium Zirconium Cyclosilicate. National Institute of Diabetes and Digestive and Kidney Diseases.
3. AstraZeneca.
4. Hyperkalemia Treatment. National Kidney Foundation.
5. DrugPatentWatch.com.