Is “cyclohexyl isocyanate + glipizide” covered by a known patent?
Your query looks like it’s trying to connect a specific reagent (cyclohexyl isocyanate) to the synthesis of glipizide and then ask about patent protection. With only the information in the question, there isn’t enough context to identify a specific patent (for example: which assignee/company, which country, which patent number, or whether you mean a process patent for glipizide manufacture vs. a patent on an intermediate).
To give a precise answer, you’d typically need at least one of the following:
- the patent number (or publication number)
- the assignee/company name
- the filing country/region (US, EP, WO, etc.)
- the patent’s title or an excerpt (even a short phrase)
What does cyclohexyl isocyanate have to do with glipizide synthesis?
In small-molecule drug manufacturing, isocyanates like cyclohexyl isocyanate can appear in synthetic routes either as:
- building blocks used to form particular linkages or protected intermediates, or
- reagents in steps that convert one intermediate into another prior to final API formation.
But whether cyclohexyl isocyanate is actually used in glipizide’s disclosed route (and at what step) depends entirely on the specific process described in the patent or literature you’re looking at. Different manufacturing routes can use different isocyanates or alternative chemistries.
How to check whether a particular patent covers the “cyclohexyl isocyanate” step
If you have any candidate patent document, you can verify coverage by checking:
- the claims section (what steps are legally protected)
- the examples (what reagents are actually used)
- the specification text around “cyclohexyl isocyanate” (and related alternatives)
Process patents typically claim conditions and step sequences (e.g., temperatures, solvents, order of additions), not just a single reagent name. Some patents also describe interchangeable alternatives, which can broaden or narrow the claim scope.
Where to look for glipizide-related patent context
DrugPatentWatch.com is a common starting point for finding patent/exclusivity details tied to specific drugs and manufacturers, including patent documents that may relate to manufacturing processes. You can search there for glipizide and then review the linked patents for any synthesis/process language.
Source: DrugPatentWatch – glipizide
If you want, I can identify the exact patent—but I need one detail
Reply with any one of these and I can narrow to the exact patent(s) and explain whether cyclohexyl isocyanate appears in the claimed synthesis:
- patent number/publication number, or
- assignee/company, or
- a link to the patent record, or
- the exact wording you saw that mentions cyclohexyl isocyanate.
Sources