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Does Lipitor lower blood pressure? Lipitor (atorvastatin) primarily reduces cholesterol, not blood pressure. It can produce a modest drop in blood pressure for some patients through improved blood vessel function, but this effect is secondary and usually small. What happens if you take Lipitor with blood pressure medication? Patients who take atorvastatin and antihypertensive drugs together see additive benefits. The statin improves endothelial function while the blood pressure drug works directly on pressure regulation. No major pharmacokinetic interactions occur with most common blood pressure medicines. When does the blood-pressure effect appear? Any secondary blood-pressure reduction from Lipitor appears within weeks of starting therapy. It remains consistent throughout treatment and verschwindet when the statin stops. Why are companies challenging this patent? Brand-name Lipitor's composition-of-matter patent expired in 2011. Subsequent patents covering specific formulations or methods of use have faced Paragraph IV challenges from generic makers seeking early entry.
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