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Zetia uses ezetimibe, a medicine that lowers cholesterol by blocking cholesterol absorption in the small intestine. As a result, less cholesterol enters the bloodstream from the gut, which helps reduce LDL (“bad”) cholesterol levels [1].
Zetia is not a statin. It is an intestinal cholesterol absorption inhibitor. Statins instead reduce cholesterol production in the liver, while Zetia targets absorption from the diet [1].
Zetia can be used alone or combined with other cholesterol-lowering treatments such as statins or bile-acid sequestrants, depending on the person’s cholesterol levels and treatment plan [1].
If Zetia is stopped, its cholesterol-lowering effect typically ends over time, and LDL cholesterol may rise again, assuming diet and other therapies remain unchanged. Your clinician may adjust treatment if cholesterol levels increase [1]. Sources [1] https://www.drugs.com/zetia.html
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