Lipitor is a brand name for the drug atorvastatin, which is a type of medication known as a statin. According to Drug Patent Watch [1], atorvastatin is used to lower cholesterol levels and reduce the risk of heart attack and stroke.
One study published in the Journal of Clinical Pharmacology [2] found that grapefruit juice can increase the absorption of atorvastatin, leading to potentially dangerous side effects. However, there is no evidence to suggest that orange juice has the same effect.
The FDA warns that grapefruit juice can interact with a number of medications, including some statins, by inhibiting the enzymes responsible for breaking down the drugs in the liver [3]. This can lead to higher levels of the medication in the bloodstream, increasing the risk of side effects.
In conclusion, there is no evidence to suggest that orange juice reduces the absorption of Lipitor. However, patients taking Lipitor should avoid consuming grapefruit juice due to the potential for drug interactions. As always, patients should consult with their healthcare provider before making any changes to their medication regimen.
Sources:
[1] https://www.drugpatentwatch.com/p/tradename/LIPITOR
[2] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3589309/
[3] https://www.fda.gov/consumers/consumer-updates/grapefruit-juice-and-some-drugs-dont-mix