According to the provided sources, there is no direct evidence that suggests skim milk affects Lipitor differently than whole milk. Lipitor is a brand name for the drug atorvastatin, which is a type of statin used to lower cholesterol levels in the blood. Statins work by inhibiting the enzyme HMG-CoA reductase, which is involved in the production of cholesterol in the liver [1].

One of the sources provided [2] is a study that investigated the effect of dairy products on the absorption of atorvastatin. The study found that the consumption of dairy products did not significantly affect the pharmacokinetics of atorvastatin. The study used whole milk, which is higher in fat than skim milk, but it is reasonable to assume that the results would be similar for skim milk.

Another source [3] explains that statins can be taken with or without food, but it is recommended to take them at the same time every day. The source does not mention any specific recommendations regarding the consumption of dairy products with statins.

In summary, there is no evidence to suggest that skim milk affects Lipitor differently than whole milk. However, it is important to follow the instructions provided by your healthcare provider and the medication label when taking Lipitor or any other medication.

Sources:
[1] https://www.drugpatentwatch.com/p/tradename/LIPITOR
[2] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4642426/
[3] https://www.heartuk.org.uk/getting-treatment/statins