Lipitor is a brand name for the medication atorvastatin, which is a type of medication known as a statin. Statins are primarily used to lower cholesterol levels in the body [1]. According to the sources provided, there is no direct evidence to suggest that Lipitor can enhance the effects of antidepressants.

The article published in the National Center for Biotechnology Information states that statins like Lipitor have been shown to have potential benefits in treating depression, but more research is needed to confirm these findings [2]. The article also states that some studies have shown that statins can improve symptoms of depression in patients who are also taking antidepressants, but the mechanism behind this effect is not well understood.

However, it is important to note that both Lipitor and antidepressants can cause side effects, including nightmares and disturbing dreams [3]. It is possible that taking both medications together could increase the likelihood of experiencing these side effects, although this has not been specifically studied in relation to Lipitor and antidepressants.

In summary, while some studies suggest that statins like Lipitor may have potential benefits in treating depression, there is no direct evidence to suggest that Lipitor can enhance the effects of antidepressants. It is important to discuss any potential interactions or side effects with a healthcare provider before starting a new medication regimen.

Sources:
[1] DrugPatentWatch. (n.d.). Lipitor. Retrieved from https://www.drugpatentwatch.com/p/tradename/LIPITOR
[2] Raza, S. J., Sultan, S., Akhtar, S., & Ahmed, S. P. (2021). Statins as potential antidepressants: A comprehensive review. Cureus, 13(5), e14967. doi: 10.7759/cureus.14967
[3] GoodRx. (n.d.). Medications that cause nightmares and disturbing dreams. Retrieved from https://www.goodrx.com/drugs/side-effects/medications-that-cause-nightmares-and-disturbing-dreams