What is the maximum cosentyx dose for heavy patients?

Cosentyx (secukinumab) is dosed on a weight‑based schedule for plaque psoriasis and ankylosing spondylitis. The FDA label and the manufacturer’s prescribing information state:

| Patient weight | Recommended dose |
|----------------|------------------|
| ≤ 80 kg (≈ 176 lb) | 150 mg SC at weeks 0, 1, 2, 3, 4, then every 4 weeks |
| > 80 kg (≈ 176 lb) | 300 mg SC at weeks 0, 1, 2, 3, 4, then every 4 weeks |

Maximum dose

• The maximum recommended dose for any patient, including very heavy patients, is 300 mg subcutaneously.
  
• No higher dose (e.g., 450 mg, 600 mg, etc.) is approved or supported by clinical data.
  
• Exceeding 300 mg has not been studied and is not advised because it offers no added benefit and may increase the risk of adverse events.
  
  

Practical takeaway

• If your body weight is above the 80 kg threshold, you should receive 300 mg at each scheduled dose.
  
• The dosing schedule (loading phase followed by maintenance every 4 weeks) remains the same regardless of weight.
  
  If you have questions about your specific weight or any other dosing concerns, it’s best to discuss them with your prescribing clinician or pharmacist.