Flexeril is a brand name for the muscle relaxant cyclobenzaprine [1]. It is prescribed to relieve muscle spasms and the associated pain that often accompanies acute, painful musculoskeletal conditions [2].
How does cyclobenzaprine work?
Cyclobenzaprine functions by acting on the central nervous system to reduce muscle spasms [2]. It is believed to exert its effects through the brainstem, reducing descending facilitatory impulses from the motor cortex and maintaining some degree of centrally mediated tonic somatic motor tone [3].
What conditions is Flexeril used for?
Flexeril is indicated for the short-term treatment of muscle spasms associated with acute, painful musculoskeletal conditions [2]. This can include injuries to muscles, ligaments, or tendons, as well as conditions like back pain or neck pain that involve muscle tightness and spasms [4].
How long does Flexeril treatment typically last?
Treatment with Flexeril is generally intended for short-term use [2]. The effectiveness of cyclobenzaprine for longer-term use has not been established, and it is typically prescribed for a period of two to three weeks [5].
What are common side effects of Flexeril?
Common side effects associated with Flexeril use include drowsiness, dizziness, dry mouth, and fatigue [2][4]. Patients may also experience blurred vision, weakness, or headaches [4]. It is important for individuals to avoid activities requiring mental alertness, such as driving or operating heavy machinery, until they know how the medication affects them [2].
What are the risks or precautions when taking Flexeril?
Due to its sedative effects, Flexeril should be used with caution in patients who may be more susceptible to these effects, such as the elderly [2]. It can also interact with other central nervous system depressants, including alcohol and certain medications [6]. Patients with a history of heart conditions, liver problems, or thyroid issues should inform their doctor before starting Flexeril [4]. The drug is also not recommended for use in the recovery phase of myocardial infarction or in individuals with arrhythmias, heart block, or conduction disturbances [2].
Can I take Flexeril with other medications?
Flexeril can interact with a variety of medications, including monoamine oxidase (MAO) inhibitors, certain antidepressants, and other central nervous system depressants [6]. It is crucial to provide a complete list of all medications, including over-the-counter drugs and herbal supplements, to a healthcare provider to avoid potentially dangerous interactions [6].
When does the patent for Flexeril expire?
Cyclobenzaprine has been available generically for many years, with its primary patents having long since expired [7]. This means that generic versions of cyclobenzaprine are widely available [1].
Who manufactures generic cyclobenzaprine?
Multiple pharmaceutical companies manufacture generic versions of cyclobenzaprine. These products are typically available through most pharmacies [1].