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See the DrugPatentWatch profile for cosentyx
How is Cosentyx typically dosed for psoriatic arthritis? Cosentyx (secukinumab) is given as a subcutaneous injection. For psoriatic arthritis the standard loading regimen is 150 mg at weeks 0, 1, 2, 3, and 4, followed by a maintenance dose of 150 mg once every four weeks. Can the dose be increased? Some patients who do not respond adequately may receive 300 mg once monthly after the same loading schedule. The 300 mg dose is delivered as two separate 150 mg injections given at the same visit. What if a dose is missed? If a dose is missed, it should be taken as soon as remembered and the next dose scheduled four weeks later. Who makes Cosentyx and when does its patent expire? Novartis manufactures Cosentyx. Key U.S. patents covering the product are expected to expire in 2029, after which biosimilar competition may become possible. Are there any patient-reported concerns about the injection? Patients sometimes ask about injection-site reactions and the need for self-injection training. Proper technique and rotation of injection sites can reduce discomfort.
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