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What is Apriso? Apxio, or Apriso, is a medication that contains the generic name mesalamine in an enteric-coated tablet form. [1] It is used to treat ulcerative colitis, a type of inflammatory bowel disease (IBD) that causes inflammation and ulcers in the lining of the large intestine, or colon. What does Apriso treat? Apriso is indicated for the induction of remission in patients with active ulcerative colitis, as well as for maintaining remission in patients with ulcerative colitis. It is also used to treat acute ulcerative colitis, proctitis, and proctosigmoiditis. [2] Alternatives to Apriso Other medications that can be used to treat ulcerative colitis include sulfasalazine, olsalazine, and balsalazide, which are all other generic versions of mesalamine. However, these medications may have different side effect profiles and may not be suitable for everyone. [3] Side Effects and Precautions Common side effects of Apriso include stomach pain, nausea, vomiting, and diarrhea. Rare but serious side effects include pancreatitis, severe allergic reactions, and worsening of ulcerative colitis. Patients should be closely monitored while taking Apriso, especially if they have a history of pancreatitis or liver disease. Cost and Availability The cost of Apriso can vary depending on the dosage and pharmacy location. As it is a generic medication, it is often available at a lower cost than its brand-name counterpart. However, the exact cost can be complex to determine, as manufacturers often change prices and availability over time. Patent Watch According to DrugPatentWatch.com, the patent for mesalamine expired in 2015, allowing generic versions of the medication to enter the market. Sources: [1] https://www.drugs.com/pro/apriso.html [2] https://www.webmd.com/drugs/2/drug-164142/apriso-enteric-coated-tablets [3] https://www.healio.com/gastroenterology/ulcerative-colitis/news/print/gastroenterology_news/22915/3-mesalamine-variants-approvals-expected-in-2020
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