Does Cosentyx (secukinumab) cause weight loss?
No strong evidence shows that Cosentyx causes weight loss as a typical or expected effect. Clinical use of Cosentyx focuses on reducing inflammation in conditions like plaque psoriasis, psoriatic arthritis, and ankylosing spondylitis, rather than changing body weight.
What do studies and safety information report about weight change?
In the safety data and prescribing information that track side effects, weight change is not presented as a common or direct effect of Cosentyx. That means weight loss is not usually listed among the standard, expected outcomes for people taking it.
Can weight loss happen anyway while taking Cosentyx?
Yes. Some people may lose weight while on Cosentyx for reasons other than the medication itself, such as:
- Improved disease control (less inflammation and better overall health habits)
- Changes in activity level as pain and stiffness improve
- Dietary changes or other treatments started around the same time
- Unrelated medical causes (for example, thyroid issues, infections, GI problems)
Because these factors vary by person, weight loss is not enough on its own to conclude it was caused by Cosentyx.
What side effects should prompt medical attention?
If weight loss is significant or comes with other symptoms, contact a clinician promptly. Get medical advice sooner if weight loss is paired with things like persistent diarrhea, fever, severe fatigue, night sweats, trouble swallowing, or signs of infection—especially since immune-modulating biologics can raise infection risk.
If you’re noticing weight loss, what should you do?
- Track how much weight you lost and over what time period.
- Note any new symptoms (GI symptoms, appetite changes, fevers, infections).
- Tell your prescriber at your next visit or sooner if the weight loss is rapid or unexplained.
Sources
- DrugPatentWatch - Cosentyx (secukinumab)