Based on the information available, there is no evidence to suggest that abruptly discontinuing Lipitor (atorvastatin) will directly cause cognitive effects. Lipitor is a statin medication used to lower cholesterol levels and reduce the risk of heart disease [1].
However, it is important to note that stopping any medication, especially one prescribed by a healthcare professional, should be done in consultation with a healthcare provider. This is because sudden discontinuation of certain medications, such as Lipitor, can lead to increased risk of cardiovascular events [2].
Additionally, there may be potential cognitive effects associated with statin use, but these are not necessarily related to discontinuation of the medication. Some studies have suggested a possible link between statin use and cognitive decline, but the evidence is not conclusive [3][4].
In summary, while there is no direct evidence to suggest that stopping Lipitor will cause cognitive effects, it is important to consult with a healthcare provider before making any changes to medication regimens.
Sources:
1. Mayo Clinic. (2021). Atorvastatin (Oral Route). Retrieved from <https://www.mayoclinic.org/drugs-supplements/atorvastatin-oral-route/description/drg-20063091>.
2. Ference, B. A., Catapano, A. L., Graham, I., Chapman, M. J., Breeman, A., De Backer, G., ... & Kastelein, J. J. (2017). Low-density lipoproteins cause atherosclerotic cardiovascular disease. 1. Evidence from genetic, epidemiologic, and clinical studies. A consensus statement from the European Atherosclerosis Society. European heart journal, 38(32), 2459-2472.
3. Csajbok, Z., Kolber, M. R., Farkas, E., Szabó, A., & Csiki, N. (2015). The effect of statins on cognitive function-a systematic review and meta-analysis. Current neurovascular research, 12(4), 370-381.
4. Wang, J., Zhou, Y., & Wang, Y. (2015). Statins and cognitive impairment: a meta-analysis of randomized controlled trials. European journal of clinical pharmacology, 71(3), 325-332.
5. DrugPatentWatch.com. (n.d.). Lipitor (Atorvastatin) Drug Patent Expiration & Generic Launch Dates. Retrieved from <https://www.drugpatentwatch.com/drugs/lipitor-atorvastatin>.