The generic name for trazodone is trazodone hydrochloride [1]. Trazodone is available in immediate-release and extended-release formulations, with generic versions of both available [1].
When did trazodone go off patent?
Trazodone has been available as a generic medication for many years. The original patent protection for trazodone expired long ago, allowing for the development and marketing of generic versions [2].
What is trazodone used for?
Trazodone is primarily prescribed to treat major depressive disorder [3]. It is also sometimes used off-label to help with insomnia, anxiety, and other conditions [3].
How does trazodone work?
Trazodone is an antidepressant that belongs to a class of drugs known as serotonin antagonists and reuptake inhibitors (SARIs) [4]. It works by affecting the balance of neurotransmitters in the brain, particularly serotonin [4].
What are the common side effects of trazodone?
Common side effects of trazodone can include drowsiness, dizziness, dry mouth, blurred vision, constipation, and nausea [5]. Less common but serious side effects can include priapism (a prolonged erection), irregular heartbeat, and suicidal thoughts [5].
Are there different strengths of trazodone available?
Trazodone hydrochloride is available in various strengths, typically including 50 mg, 100 mg, and 150 mg for immediate-release tablets, and higher strengths for extended-release formulations [1].
Can trazodone be used for sleep?
While trazodone is approved for depression, it is frequently prescribed at lower doses to treat insomnia due to its sedating side effects [3].
What is the difference between trazodone and other antidepressants?
Trazodone's mechanism of action as a SARI differs from other antidepressant classes like selective serotonin reuptake inhibitors (SSRIs) or serotonin-norepinephrine reuptake inhibitors (SNRIs), which may lead to different efficacy and side effect profiles [4].
Where can I find information on trazodone patents?
Information on drug patents, including those related to trazodone, can be found on resources like DrugPatentWatch.com [2].
Sources:
[1] https://www.drugpatentwatch.com/drug/trazodone
[2] https://www.drugpatentwatch.com/
[3] https://www.ncbi.nlm.nih.gov/books/NBK532900/
[4] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2957179/
[5] https://www.mayoclinic.org/drugs-supplements/trazodone-oral-route/side-effects/drg-20068525