Can I take Magnesium with Lisinopril?

Magnesium and lisinopril are two commonly prescribed medications that can interact with each other when taken together. Lisinopril, an angiotensin-converting enzyme (ACE) inhibitor, is used to treat high blood pressure and heart failure [1]. Magnesium, on the other hand, is a mineral supplement often used to treat magnesium deficiencies or as a complementary therapy for various conditions [2].

One main concern when taking magnesium with lisinopril is the potential decrease in blood pressure. ACE inhibitors like lisinopril lower blood pressure by relaxing blood vessels and reducing the amount of angiotensin II, a potent vasoconstrictor. When taken with magnesium, these effects may be enhanced, potentially leading to hypotension (low blood pressure) [3].

However, this interaction requires careful monitoring by a healthcare provider. While there have been no comprehensive studies examining the interaction between magnesium and lisinopril, research suggests that concurrent use can lead to increased magnesium levels in the blood, but the risk of hypotension is generally mild [4].

It is crucial to consult with your doctor or pharmacist before taking magnesium with lisinopril. If you do choose to use both medications, monitor your blood pressure closely. Be aware that taking too much magnesium can cause gastrointestinal side effects, such as diarrhea or stomach cramps [5].

As a precautionary measure, you can start with a low dose of magnesium and gradually increase it as needed under your healthcare provider's supervision.

References:

1. https://www.drugs.com/lisinopril.html
2. https://www.drugs.com/mg/magnesium-polyethylene-glycol.html
3. https://www.ncbi.nlm.nih.gov/books/NBK470572/
4. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4425558/
5. https://www.drugs.com/sfx/magnesium-polyethylene-glycol-side-effects.html