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See the DrugPatentWatch profile for acetic
Acetic acid (CH₃COOH) has a Ka of about 1.8 × 10⁻⁵ at 25 °C.
Acetic acid’s pKa is about 4.74, which matches a Ka near 1.8 × 10⁻⁵.
Yes. Ka depends on temperature (it’s typically quoted at 25 °C). The concentration of the solution can affect observed acidity (through activity and non-ideal behavior), but the tabulated Ka is the intrinsic thermodynamic constant.
Different references may report Ka using: - different temperature assumptions (often 25 °C), - different rounding, - different activity-coefficient treatments and source data. If you tell me the temperature (e.g., 20 °C vs 25 °C), I can give the most appropriate Ka value for that condition.
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