Acyclovir is an antiviral medication that is used to treat infections caused by the herpes virus, while antibiotics are used to treat bacterial infections. According to the sources provided, there are no known interactions between acyclovir and antibiotics. Therefore, it is generally safe to take acyclovir with antibiotics.

However, it is important to note that acyclovir may interact with other medications, such as probenecid and cimetidine, which can increase the concentration of acyclovir in the blood and increase the risk of side effects. Additionally, individuals with kidney disease may need to have their dosage of acyclovir adjusted.

It is important to follow the dosage and administration instructions provided by a healthcare professional when taking acyclovir and antibiotics together. If any side effects or concerns arise, it is recommended to consult with a healthcare provider.

Sources:
[1] https://www.drugpatentwatch.com/p/tradename/ACYCLOVIR
[2] https://www.mayoclinic.org/drugs-supplements/acyclovir-oral-route-intravenous-route/precautions/drg-20068393?p=1
[3] https://www.healthcentral.com/article/acyclovir-amoxicillin-together