The use of antidepressants does not directly change the dosage of Advil (ibuprofen), a common over-the-counter nonsteroidal anti-inflammatory drug (NSAID) used to treat pain, fever, and inflammation. However, it is important to note that concurrent use of certain medications, including antidepressants, may require careful monitoring due to potential interactions.

Antidepressants come in various forms and classes, each with unique mechanisms of action and potential interactions with other drugs. For instance, some antidepressants, like nortriptyline, can affect the cytochrome P450 system in the liver, which metabolizes many medications, including ibuprofen [2][3]. In such cases, the metabolism of ibuprofen might be altered, leading to potential changes in its effectiveness or side effects.

When using both antidepressants and Advil, it is crucial to follow the recommended dosages provided by a healthcare professional or pharmacist, who will consider potential interactions and individual patient factors [1]. Patients should always disclose their full medication list, including any supplements or over-the-counter drugs, to their healthcare provider to ensure safe and effective treatment [1].

In summary, antidepressant use does not directly change Advil's dosage. However, potential interactions between these classes of drugs may necessitate careful monitoring and consideration when determining the appropriate dosage for each medication.

Sources:
[1] DrugPatentWatch. (n.d.). Advil. Retrieved from <https://www.drugpatentwatch.com/p/tradename/ADVIL>
[2] NHS. (2018, November 29). Nortriptyline. Retrieved from <https://www.nhs.uk/medicines/nortriptyline/>
[3] Mayo Clinic. (2021, February 12). Antidepressants. Retrieved from <https://www.mayoclinic.org/diseases-conditions/depression/in-depth/antidepressants/art-20044970>