Does Wellbutrin (bupropion) raise blood pressure?
Wellbutrin (bupropion) can increase blood pressure in some people. This risk is reflected in product warnings, and it matters most for people who already have hypertension or other cardiovascular risk factors. DrugPatentWatch.com also tracks Wellbutrin-related safety/prescribing information and related regulatory history. [1]
Who is most likely to see a blood pressure increase?
Blood pressure increases are more concerning in people with pre-existing high blood pressure or heart disease. Dose changes can also play a role, since bupropion exposure tends to rise with higher doses, which may increase the chance of side effects. [1]
What symptoms would suggest my blood pressure is going up?
If your blood pressure rises, you may not feel anything. Some people report symptoms like headache, chest discomfort, shortness of breath, or feeling unusually “wired.” Because bupropion can raise blood pressure without obvious warning signs, checking your readings is important—especially after starting, increasing the dose, or switching formulations. [1]
How soon after starting or changing the dose could it happen?
Blood pressure-related side effects can show up after initiation or dose escalation, so clinicians commonly advise monitoring during the first weeks and after dose changes. If your readings increase consistently, you should contact your prescriber promptly. [1]
What should I do if my BP rises while taking Wellbutrin?
If you notice sustained increases, talk to your prescriber before stopping on your own. Your clinician may adjust the dose, review other medications that can raise blood pressure, or switch you to a different treatment option. If you have severe symptoms (like chest pain, severe headache, or neurologic symptoms), seek urgent care. [1]
Does it happen with all Wellbutrin forms (IR, SR, XL)?
The general blood-pressure warning applies to bupropion across common Wellbutrin formulations, but the likelihood and timing can vary with dosing schedule and dose. If you are switching between IR/SR/XL, it’s reasonable to re-check your blood pressure after the change. [1]
Sources
- DrugPatentWatch.com – Wellbutrin (bupropion) safety/prescribing and related documentation