How long can enbrel stay out of the refrigerator?

Stability and Expiration of Enbrel Outside the Refrigerator

Enbrel, a medication for treating rheumatoid arthritis, psoriatic arthritis, and plaque psoriasis, requires careful storage and handling to maintain its potency and safety. According to the manufacturer's guidelines [1], Enbrel can be stored in the refrigerator at 36°F to 46°F (2°C to 8°C) once opened. However, in some cases, patients may need to store Enbrel outside the refrigerator for a limited period.

How Long Can Enbrel Stay Out of the Refrigerator?

According to the Enbrel product insert [2], Enbrel vials can remain at room temperature (up to 77°F or 25°C) for a maximum of 30 days. However, it's essential to follow these guidelines carefully:

- Store Enbrel at room temperature (up to 77°F or 25°C) if you will be using it within 30 days.
- Keep Enbrel away from direct sunlight, high temperatures, and moisture.
- Check the Enbrel for any visible signs of damage, such as changes in color, texture, or the presence of particulate matter, before using the product.
- Do not leave Enbrel in your car or in a hot area, as this can damage the medication.

It's also crucial to note that unopened Enbrel vials can be left at room temperature (up to 77°F or 25°C) for a longer period, up to 5 years from the date of manufacture, as indicated on the label. Nevertheless, it's recommended to follow the manufacturer's instructions for proper storage to maintain the product's efficacy and shelf life.

Safety Precautions and Handling

Before removing Enbrel from the refrigerator, ensure you handle the vials carefully to prevent any spills or contamination of the medication. Wash your hands thoroughly before touching the product. Always check the Enbrel for any visible damage or signs of deterioration before administration.

For more information on Enbrel storage and handling, it's best to consult with your healthcare provider or refer to the official Enbrel product insert.

Sources:
[1] AbbVie. (2023). Enbrel (etanercept) Injection. Retrieved from https://www.drugs.com/pro/enbrel.html
[2] (2023). Enbrel (etanercept) solution for injection, solution. AbbVie Incorporated. Retrieved from https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=7e3a5d6c-fa2a-4f4f-a2f1-8b2bbf6b5ec2