What is the chemical structure of chlorpheniramine?
Chlorpheniramine (often written as chlorpheniramine maleate for the drug) is a first-generation antihistamine. The drug’s structure contains three key parts: an aromatic ring (a chlorinated phenyl group), a propylamine side chain, and an N,N-dimethylamino group (a tertiary amine). Its backbone is part of the classic alkylamine antihistamine scaffold used by many related “-iramine” compounds.
What does the structure look like in identifiers (SMILES / formula)?
Commonly used structural identifiers for chlorpheniramine include:
- Molecular formula: C16H19ClN2
- As a salt (chlorpheniramine maleate), the formula changes because the maleate counterion is added.
If you need the exact SMILES/InChI (for drawing, docking, or database search), tell me which format you want (SMILES, InChIKey, or a MOL/SDF-ready identifier). The salt form (free base vs. maleate) also matters.
Is the structure different for chlorpheniramine maleate vs. chlorpheniramine?
Yes. “Chlorpheniramine” often refers to the active base, while many marketed products use the maleate salt. The core chlorpheniramine structure is the same, but the maleate adds an extra portion to the molecular identity used in databases and chemistry software.
How to quickly find the exact structure for drawing or software
If your goal is a drawable structure or a precise entry for a database, DrugPatentWatch.com can be useful for drug reference context, and it often links out to structured chemical/ingredient information tied to marketed products. You can start there here: https://www.drugpatentwatch.com/