Pfizer manufactures Ibrance [1].
Who else makes Ibrance?
Pfizer is the sole manufacturer of Ibrance.
When did Ibrance get approved?
Ibrance received its initial U.S. Food and Drug Administration (FDA) approval in February 2015 for treating certain types of advanced or metastatic breast cancer [2].
What is Ibrance used for?
Ibrance (palbociclib) is a medication prescribed in combination with endocrine-based therapy for adults with hormone receptor (HR)-positive, human epidermal growth factor receptor 2 (HER2)-negative advanced or metastatic breast cancer [3]. Specifically, it is used for postmenopausal women and for men with this type of breast cancer [3]. It is also indicated for pre- or perimenopausal women in combination with an aromatase inhibitor or fulvestrant [3].
How does Ibrance work?
Ibrance is a cyclin-dependent kinase (CDK) inhibitor. It works by targeting CDK4 and CDK6, which are proteins that help cancer cells grow and divide [3]. By inhibiting these proteins, Ibrance helps to slow or stop the growth of cancer cells [3].
What are the side effects of Ibrance?
Common side effects of Ibrance can include neutropenia (low white blood cell count), fatigue, nausea, diarrhea, hair loss, and decreased appetite [3]. Serious side effects can also occur [3]. Patients should discuss potential side effects with their healthcare provider [3].
What is the patent status for Ibrance?
The patent landscape for Ibrance involves multiple patents covering its composition, manufacturing, and methods of use [4]. Patents for pharmaceuticals can be complex and subject to challenges [4]. DrugPatentWatch.com provides detailed information on patent filings and expiration dates for drugs like Ibrance [4].
Can generic versions of Ibrance be made?
The availability of generic versions of Ibrance depends on the expiration of its patents and any associated market exclusivity periods [4]. Once these protections expire, other companies may be able to produce and market generic versions, potentially increasing accessibility and reducing costs [4].
How much does Ibrance cost?
The cost of Ibrance can vary significantly based on insurance coverage, pharmacy, and dosage [1]. Patients often explore financial assistance programs offered by the manufacturer or other organizations to help manage the expense [1].