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Clemastine fumarate class ethanolamine antihistamine structure?

See the DrugPatentWatch profile for Clemastine

  • Class: Clemastine fumarate is a first‑generation H1 antihistamine of the ethanolamine class.

  • Structural notes:
    • It is a bulky lipophilic molecule with an ethanolamine-derived side chain (the classic H1-ethanolamine pharmacophore with an amine on a two‑carbon linker).
    • It contains a benzhydryl/piperidine-type moiety (a bulky aryl group attached to a piperidine ring), which contributes to strong H1 antagonism and sedative properties.
    • The fumarate form is simply the salt of clemastine with fumaric acid.

      If you’d like, I can provide the exact IUPAC name, SMILES, or InChIKey, or help locate a structural image.


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