What is the cost of entresto?

How much does Entresto cost without insurance?

Entresto tablets cost between $600 and $750 per month for the average patient at retail pharmacies. Prices vary by dose and location, with the 24/26 mg tablet priced around $15 per tablet and the 97/103 mg tablet at approximately $18 per tablet. These figures are approximate and reflect 2024 retail prices.

Why do prices vary so much across pharmacies?

Local pharmacy chains and online retailers sometimes offer discounts through coupons or membership programs. GoodRx coupons bring the price down to $550–$650 per month. SingleCare and similar services provide similar discounts. Pharmacy choice and ZIP code often determine the actual price a patient pays.

What does insurance coverage look like for Entresto?

Most commercial insurance plans cover Entresto under Tier 3 or Tier 4, requiring a copay of $50–$100 per month. Medicare Part D plans show mixed coverage. Some require prior authorization or step therapy before approving coverage. Patients on Medicaid report low or zero copays in many states.

When does Entresto’s patent expire?

The primary compound patent expires in 2026. Several secondary patents covering formulations and methods of use extend protection into 2027 and 2028. Biosimilar or generic versions are not expected before 2027 at the earliest.

How does Entresto compare in price to other heart failure drugs?

Entresto sits above average among heart failure medications. Valsartan costs about $15–$20 per month, metoprolol around $10–$15, and generic lisinopril under $10. Entresto remains 20 times more expensive than these older agents.