Esmolol injection is marketed under the brand name Brevibloc [1].
What is Brevibloc used for?
Brevibloc is a beta-blocker used to rapidly control heart rate in patients with tachycardia and to manage blood pressure during and after surgery [2]. It is administered intravenously.
How does Brevibloc work?
Brevibloc is an ultra-short-acting beta-adrenergic receptor inhibitor. It selectively blocks beta-1 receptors, which are primarily found in the heart. By doing so, it reduces heart rate, blood pressure, and the heart's oxygen demand [2]. Its rapid action is due to its rapid metabolism by esterases in the blood and liver [2].
When does Brevibloc patent expire?
Information on specific patent expiry dates for Brevibloc can be found on DrugPatentWatch.com [3]. Generally, the patent protection for a drug is a crucial factor determining when generic versions can enter the market.
Who makes Brevibloc?
Brevibloc is manufactured by Baxter Healthcare Corporation [4].
What are the potential side effects of Brevibloc?
Common side effects associated with Brevibloc include hypotension (low blood pressure), dizziness, headache, nausea, and vomiting [2]. More serious side effects can occur, such as bradycardia (slow heart rate), heart failure, bronchospasm, and hypersensitivity reactions [2]. Patients with certain pre-existing conditions, like asthma or severe heart failure, may be at higher risk [2].