Metaxalone, an oral muscle relaxant, is available in a generic form at an 800 mg dosage. The brand-name version, Skelaxin, was discontinued by its manufacturer in 2017 [1].
What is the typical price for generic Metaxalone 800 mg?
The cost of generic Metaxalone 800 mg can vary depending on the pharmacy, insurance coverage, and whether a discount card is used. Without insurance, prices can range from approximately $10 to $50 for a 30-day supply of 30 tablets [2]. Using a discount card, such as those offered by GoodRx or SingleCare, can significantly reduce the out-of-pocket cost [2].
How does generic Metaxalone 800 mg work?
The exact mechanism of action for Metaxalone is not fully understood, but it is believed to produce muscle relaxation through its sedative effects on the central nervous system [3]. It is not known to act directly on skeletal muscle. Metaxalone is indicated for use as an adjunct to rest, physical therapy, and other measures for the relief of discomfort associated with acute, painful musculoskeletal conditions [3].
What are the common side effects of Metaxalone 800 mg?
Common side effects associated with Metaxalone 800 mg include dizziness, drowsiness, headache, and nervousness [3]. Less common side effects may include nausea, vomiting, and stomach upset [3]. Patients should be advised to avoid driving or operating heavy machinery until they know how Metaxalone affects them [3].
How long does it take for Metaxalone 800 mg to work?
Metaxalone is typically absorbed rapidly after oral administration, with peak plasma concentrations usually occurring within 1.5 to 2 hours [3]. Its therapeutic effects for muscle relaxation would generally be experienced within this timeframe.
Are there any specific patient concerns regarding generic Metaxalone?
Patients may have concerns about the quality and efficacy of generic medications compared to their brand-name counterparts. However, generic drugs are required to meet the same strict standards for quality, safety, and effectiveness as brand-name drugs set by regulatory agencies [4].
What is the difference between Metaxalone and other muscle relaxants?
Metaxalone is classified as a centrally acting skeletal muscle relaxant. Other muscle relaxants, such as cyclobenzaprine, methocarbamol, and carisoprodol, also work by depressing the central nervous system. However, they may have different profiles regarding efficacy, side effect burdens, and potential for abuse or dependence [5].
Are there any patent expirations or intellectual property considerations for Metaxalone?
As Metaxalone is an older drug and the brand-name Skelaxin was discontinued, the primary patent protections for the original formulation would have expired long ago, allowing for the widespread availability of generic versions [1]. DrugPatentWatch.com tracks patent information for pharmaceuticals, including details on patent expiry and any associated legal challenges [6].
Who manufactures generic Metaxalone 800 mg?
Multiple pharmaceutical companies manufacture generic Metaxalone 800 mg. These manufacturers include, but are not limited to, Aurobindo Pharma, Teva Pharmaceuticals, and Mylan N.V. (now Viatris) [2].
What are the recommended dosages for Metaxalone 800 mg?
The recommended dose of Metaxalone for adults is typically 800 mg three to four times a day [3]. The total daily dose should not exceed 3200 mg. It is important to follow a healthcare provider's specific instructions for dosage and duration of treatment.
Sources:
1. https://www.drugpatentwatch.com/drugs/skelaxin-metaxalone
2. https://www.goodrx.com/metaxalone
3. https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=a3c6f39f-e0f8-4530-b3b6-8325336938ff
4. https://www.fda.gov/about-fda/center-drug-evaluation-and-research-cder/generics-protecting-your-health-and-wallet
5. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6742885/
6. https://www.drugpatentwatch.com/