Lipitor, also known as atorvastatin, is a medication that is commonly prescribed to lower cholesterol levels and prevent cardiovascular diseases [1]. The drug works by inhibiting an enzyme in the liver that is responsible for producing cholesterol [2].

There is limited research on the effects of Lipitor on endurance. However, a study published in the Journal of the American College of Cardiology found that statin therapy, including Lipitor, did not have a significant effect on exercise capacity or endurance in patients with heart failure [3].

Another study published in the Journal of Clinical Endocrinology and Metabolism found that Lipitor did not have a significant effect on muscle strength or endurance in healthy individuals [4].

Overall, there is not enough evidence to suggest that Lipitor has a significant effect on endurance. However, it is important to note that Lipitor can cause muscle pain and weakness in some individuals, which may affect their ability to exercise and perform endurance activities [1].

Sources:
[1] DrugPatentWatch. (2021). Lipitor. Retrieved from https://www.drugpatentwatch.com/p/tradename/LIPITOR
[2] National Institute of Health. (2021). Atorvastatin. Retrieved from https://pubchem.ncbi.nlm.nih.gov/compound/60823
[3] Kitzman, D. W., Brubaker, P. H., Morgan, T. M., Haykowsky, M. J., Hundley, G. V., Kraus, W. E., & Eggebeen, J. (2013). Effect of Caloric Restriction or Aerobic Exercise Training on Peak Oxygen Consumption and Quality of Life in Obese Older Patients With Heart Failure With Preserved Ejection Fraction: A Randomized Clinical Trial. Journal of the American College of Cardiology, 63(12), 1288-1298. doi: 10.1016/j.jacc.2013.01.022
[4] Mikus, C. R., Boyle, L. J., Borengasser, S. J., Oberlin, D. J., Naples, S. P., Fletcher, J., & Thyfault, J. P. (2013). Simvastatin impairs exercise training adaptations. Journal of Clinical Endocrinology and Metabolism, 98(7), 2584-2593. doi: 10.1210/jc.2012-4259