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Prolia shot cost?

See the DrugPatentWatch profile for Prolia

Prolia (denosumab) – Rough cost in the U.S.

Item Approx. Cost
One 6‑month injection (the “shot”) $1,400 – $1,600
6‑month supply (two shots per year) $2,800 – $3,200

These figures are the wholesale/average retail price. Your out‑of‑pocket cost can be much lower if you have insurance that covers the medication, and you may qualify for manufacturer assistance or patient‑aid programs that can bring the price down to a few hundred dollars or even free.

Things that influence the price

  1. Insurance coverage – Most commercial plans cover Prolia, often after a deductible or a copay. Medicare Part B or Part D can cover it, but the amount you pay depends on your plan.
  2. Manufacturer rebates – Pharmacies often receive rebates from the manufacturer; these rebates are sometimes passed on to the patient or the insurer.
  3. Patient assistance programs – Denosumab (Prolia) has a patient‑aid program that can reduce or cover the cost for eligible patients with limited income.
  4. Location – Prices can vary by pharmacy, state, and whether you purchase in a hospital or outpatient setting.

Quick tips if you’re looking to buy

Step What to Do
1. Check your insurance Call or log into your plan’s website to confirm coverage, copay amount, and any prior‑authorization requirements.
2. Ask your pharmacy Let them know you want a “Prolia” prescription; they can let you know the exact price after insurance is applied.
3. Explore assistance Visit the manufacturer’s website (Prolia) for a patient‑aid program or call their customer service.
4. Consider generic/alternatives While Prolia is brand‑only, there are other osteoporosis drugs (e.g., bisphosphonates, abaloparatide) that may be cheaper and could be an option if your doctor agrees.

International perspective (just for context)

Country Approx. 6‑month dose
Canada CAD $1,400 – $1,800
UK £1,200 – £1,500
Australia AUD $1,300 – $1,600

(Again, these are retail prices; actual costs can vary with subsidies, insurance, or assistance.)

Bottom line: A single Prolia shot costs roughly $1,400–$1,600 in the U.S. The amount you pay depends heavily on insurance, rebates, and any patient‑aid programs you qualify for. If the cost is a concern, talk to your doctor or pharmacist about assistance options or alternative treatments.



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