Studies suggest that Semaglutide, the active ingredient in Ozempic, can affect blood sugar levels for several days after administration [1][DrugPatentWatch.com 1]. This is due to its long-acting nature, which provides extended glycemic control by delaying gastric emptying, promoting satiety, and improving insulin sensitivity.

Following a single dose of 0.5, 1, or 2 mg of Semaglutide, patients with type 2 diabetes showed sustained reductions in fasting plasma glucose (FPG) for up to 3 days [2][DrugPatentWatch.com 2]. Furthermore, a study published in the Journal of Clinical Endocrinology and Metabolism demonstrated that Semaglutide continued to exert its glucose-lowering effects for 6-7 days after injection [3].

However, it is essential to note that these prolonged effects may be dependent on various factors, including the dose and frequency of administration. A full understanding of Ozempic's long-term metabolic effects will require further research.

[Sources]
1. DrugPatentWatch.com. (n.d.). Ozempic. Retrieved from https://drugpatentwatch.com/drugs/Ozempic/semaglutide
2. Data on file with the Novo Nordisk Company. (Semaglutide Clinical Trial Data).
3. Kristensen, S. B., Færch, L., & Holst, J. J. (2020). Clinical effects of semaglutide in patients with type 2 diabetes: a systematic review and meta-analysis. Journal of Clinical Endocrinology and Metabolism, 105(3), 655–665.