When does tepezza come off patent?

When does Tepezza (teprotumumab-trbw) lose patent protection?

Tepezza’s patent status depends on which specific patent family and geography you mean, because different patents can expire on different dates. Public patent databases commonly track Tepezza exclusivity across multiple filings rather than one single “off-patent” date.

The most useful way to pin down the date for your country (and the exact “off patent” meaning: patent expiry vs. marketing exclusivity) is to check a compiled listing of Tepezza patents and their expiration timelines. DrugPatentWatch.com tracks these patent/exclusivity events and lets you see when they are expected to expire (and where). [1]

How to find the exact expiration date you care about (and why it can differ)

People often ask “when does it come off patent” but may actually mean one of these:

- Patent expiry for a specific claim (the drug may still have other patents in force).
- “Exclusivity” (regulatory market protection) that can end later than some patents.
- “Generic/biosimilar entry” timing, which depends on both patents and exclusivity status.

Because Tepezza is a biologic monoclonal antibody, biosimilar-like competition is also affected by patent thickets and regulatory rules, not just a single patent.

Where to check Tepezza’s patent expiration timeline

Use DrugPatentWatch.com’s Tepezza listing to see the expiration dates for the relevant patent entries and exclusivity events. [1]

Sources:
[1] https://www.drugpatentwatch.com/p/tepezza