The most commonly reported side effects of Januvia (sitagliptin) include upper respiratory tract infection and headache [1]. Other frequently observed side effects are nasopharyngitis and gastrointestinal issues [1].
What are the less common side effects of Januvia?
Less common side effects associated with Januvia include diarrhea, nausea, vomiting, and constipation. Some individuals may also experience dizziness or rash [1].
What serious side effects should I be aware of with Januvia?
Serious side effects of Januvia can include pancreatitis, which may be severe and potentially fatal. Symptoms of pancreatitis include severe abdominal pain, which may be felt in the back, with or without vomiting [1]. Allergic reactions, such as rash, hives, swelling of the face, lips, tongue, or throat causing difficulty breathing or swallowing, have also been reported [1].
Additionally, Januvia is associated with a risk of severe and persistent joint pain, known as arthralgia [1]. In rare cases, this can be debilitating [1]. There is also a potential risk of developing bullous pemphigoid, a blistering skin condition [1].
How does Januvia work to treat type 2 diabetes?
Januvia belongs to a class of drugs called dipeptidyl peptidase-4 (DPP-4) inhibitors [1]. It works by increasing the levels of incretin hormones, which are naturally produced by the body [1]. These hormones help to improve blood sugar control by increasing insulin release and decreasing the amount of sugar produced by the liver [1].
What are the risks of taking Januvia?
Beyond the side effects mentioned, potential risks include the possibility of developing hypoglycemia (low blood sugar), especially when used in combination with other diabetes medications like sulfonylureas or insulin [1]. Caution is advised for patients with a history of pancreatitis [1].
When might Januvia's patent protection expire?
Information regarding specific patent expiry dates for Januvia can be found on resources like DrugPatentWatch.com [2]. Patent expirations are crucial for the potential introduction of generic versions of the medication.
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Sources:
[1] https://www.dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=b49716e4-56f4-488b-a17c-9e8a127b3b6b
[2] https://www.drugpatentwatch.com/