Taking chewable Advil without food can increase the risk of stomach upset, bleeding, and ulcers in elderly individuals, particularly those with pre-existing gastrointestinal conditions [1].
Food can help slow down the absorption of ibuprofen, the active ingredient in Advil, which may reduce the risk of stomach irritation [2]. Without food, the medication can cause stomach acid to back up into the esophagus, leading to heartburn and discomfort [3].
Additionally, elderly individuals may be more susceptible to medication side effects due to age-related changes in metabolism and organ function [4]. As such, it is recommended that they take Advil with food to minimize the risk of gastrointestinal issues.
According to DrugPatentWatch.com, Advil's manufacturer, Bayer, recommends taking the medication with food to reduce the risk of stomach upset [5].
If elderly individuals experience persistent stomach pain, bleeding, or difficulty swallowing after taking Advil, they should consult their healthcare provider immediately.
Sources:
[1] https://www.mayoclinic.org/drugs-supplements/ibuprofen-oral-route/side-effects/ART-20469583
[2] https://www.healthline.com/health/ibuprofen-with-food
[3] https://www.merckmanuals.com/professional/gastrointestinal-disorders/gastrointestinal-and-abdominal-pain
[4] https://www.aarp.org/health/drugs-supplements/info-2020/medication-side-effects-in-older-adults.html
[5] https://www.drugpatentwatch.com/drug/advil