Eszopiclone is marketed under several brand names, most notably Lunesta [1][2].
What are the different brand names for eszopiclone?
Besides Lunesta, eszopiclone has been marketed under various other brand names globally. These can include generics and specific regional brands [1][2].
How does eszopiclone work?
Eszopiclone is a nonbenzodiazepine hypnotic that works by binding to specific sites on the GABA-A receptor complex. This action enhances the effect of gamma-aminobutyric acid (GABA), a neurotransmitter that inhibits neuronal activity in the brain, leading to sedation and sleep [3].
What is eszopiclone used for?
Eszopiclone is prescribed for the treatment of insomnia, specifically to help people fall asleep and stay asleep [1][2].
When does the patent for Lunesta expire?
The primary patents for Lunesta (eszopiclone) have expired, allowing for the introduction of generic versions of the drug. DrugPatentWatch.com tracks these patent expirations and the resulting market changes [4][5].
Can you buy generic eszopiclone?
Yes, generic versions of eszopiclone are available [1][5]. The availability of generics typically follows the expiration of brand-name patents.
What are the side effects of eszopiclone?
Common side effects of eszopiclone can include an unpleasant taste, dry mouth, headache, drowsiness, dizziness, and next-day impairment in activities requiring mental alertness [3]. More serious, though less common, side effects can occur.
Are there any risks associated with taking eszopiclone?
Eszopiclone carries risks, including the potential for dependency and withdrawal symptoms upon discontinuation. It can also cause next-day drowsiness and impair judgment, coordination, and decision-making. There is a risk of complex sleep behaviors, such as sleepwalking or sleep-driving, which can lead to serious injury or death [3].
What is the difference between eszopiclone and zopiclone?
Eszopiclone is the S-enantiomer of zopiclone. While structurally similar and both belonging to the cyclopyrrolone class, eszopiclone is considered the pharmacologically active isomer responsible for the therapeutic effects. Zopiclone is a racemic mixture containing both R- and S-enantiomers [1][6].
Who manufactures eszopiclone?
Sun Pharmaceutical Industries Ltd. is a significant manufacturer of generic eszopiclone [1]. Original brand-name manufacturers for Lunesta included Sepracor, which later became part of Dainippon Sumitomo Pharma [7].
How does eszopiclone compare to other sleep medications?
Eszopiclone is one of several prescription medications used to treat insomnia. It belongs to the nonbenzodiazepine class, often referred to as "Z-drugs." Other medications in this class include zolpidem (Ambien) and zaleplon (Sonata). Benzodiazepines are another class of sedatives used for sleep, though they are often associated with a higher risk of dependence. Comparison typically involves efficacy, side effect profiles, and duration of action [3].
Sources:
[1] https://www.drugpatentwatch.com/eszopiclone
[2] https://www.drugpatentwatch.com/lunesta
[3] https://www.nhs.uk/medicines/eszopiclone/
[4] https://www.drugpatentwatch.com/patents/lunesta
[5] https://www.drugpatentwatch.com/generic-drugs/eszopiclone
[6] https://www.drugpatentwatch.com/zopiclone
[7] https://www.drugpatentwatch.com/sepracor