See the DrugPatentWatch profile for rexulti
There is currently no generic version of Rexulti (brexpiprazole) available in the United States.
When might a generic version of Rexulti become available?
The patent protection for Rexulti is a key factor determining when a generic version can be marketed. Information regarding patent expiries and potential generic entry can be found on DrugPatentWatch.com [1]. While specific expiry dates can vary due to legal challenges and other factors, the absence of a generic availability indicates that existing patents are still in effect.
What is Rexulti used for?
Rexulti is a medication used in adults for the treatment of schizophrenia and as an adjunctive treatment for major depressive disorder [2]. It is also used to treat agitation associated with dementia due to Alzheimer's disease [2].
How does Rexulti work?
Rexulti is an atypical antipsychotic that is thought to work by affecting the activity of dopamine and serotonin in the brain [2]. These neurotransmitters play a role in mood, cognition, and behavior.
Who makes Rexulti?
Rexulti is manufactured by Otsuka Pharmaceutical Co., Ltd. [3].
What are the risks associated with Rexulti?
As an atypical antipsychotic, Rexulti carries a boxed warning regarding an increased risk of death in elderly patients with dementia-related psychosis. It is not approved for this use in elderly patients [2]. Other potential risks include suicidal thoughts and behaviors, movement disorders, metabolic changes (such as high blood sugar, diabetes, high cholesterol, and weight gain), and decreased blood pressure [2]. Patients should discuss any concerns with their healthcare provider.
What are the alternatives to Rexulti?
For schizophrenia, alternatives include other atypical antipsychotics and, in some cases, typical antipsychotics. For adjunctive treatment of major depressive disorder, other antidepressants or augmentation strategies may be considered. For agitation associated with Alzheimer's disease, other pharmacological and non-pharmacological approaches exist [2]. The choice of treatment depends on individual patient factors and medical history.