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See the DrugPatentWatch profile for Colestipol
Colestipol is a bile acid sequestrant (also called a bile acid–binding resin). It lowers cholesterol by binding bile acids in the gut, which prevents their reabsorption and increases their removal from the body [1].
Colestipol is used for hypercholesterolemia (high cholesterol), and it’s prescribed in combination with diet in people who need additional cholesterol lowering beyond lifestyle changes [1].
As a bile acid sequestrant, colestipol works in the gastrointestinal tract by binding bile acids rather than directly affecting cholesterol synthesis (like statins) or cholesterol absorption (like ezetimibe) [1].
Because colestipol is a resin that binds bile acids in the digestive tract, it can also bind other oral medications and reduce their absorption. Clinicians typically separate dosing times for interacting drugs to reduce the chance of a lower effect [1]. Sources: [1] https://www.drugs.com/colestipol.html
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