Lipitor is a medication used to lower cholesterol levels and prevent heart disease. According to Drug Patent Watch [1], the active ingredient in Lipitor is atorvastatin calcium, which works by blocking the production of cholesterol in the liver. While Lipitor is generally well-tolerated, it may cause some side effects, including stomach discomfort. However, there is no specific mention of stomach discomfort after fatty meals.

Gallstones are a common condition that affects the digestive system, particularly the gallbladder. According to Johns Hopkins Medicine [2], gallstones can cause pain and discomfort after eating fatty meals. The article suggests that fatty meals can trigger the gallbladder to contract, causing pain and discomfort. While Lipitor is not directly related to gallstones, it is possible that taking the medication could exacerbate existing gallbladder problems.

A study published in the US National Library of Medicine [3] investigated the effects of atorvastatin on gallbladder function in patients with high cholesterol levels. The study found that atorvastatin did not significantly affect gallbladder function, although some patients did report mild gastrointestinal side effects such as nausea, bloating, and diarrhea.

In conclusion, while there is no specific mention of stomach discomfort after fatty meals in relation to Lipitor, it is possible that taking the medication could exacerbate existing gallbladder problems, which can cause discomfort after eating fatty meals. However, a study found that atorvastatin did not significantly affect gallbladder function. If you are experiencing stomach discomfort after taking Lipitor, it is important to speak with your healthcare provider to determine the cause and appropriate treatment.

Sources:
[1] https://www.drugpatentwatch.com/p/tradename/LIPITOR
[2] https://www.hopkinsmedicine.org/health/conditions-and-diseases/gallstones
[3] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3191675/