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See the DrugPatentWatch profile for Tetrabenazine
When does tetrabenazine patent expiry? The original patent for tetrabenazine, also known by the brand name Xenazine, expired in 2008 [1]. However, additional patents related to specific formulations or methods of use can extend market exclusivity. DrugPatentWatch.com tracks these patents, which can be complex and may involve multiple filings [2]. What are the uses of tetrabenazine? Tetrabenazine is primarily prescribed to manage chorea, involuntary jerky movements that can occur in individuals with Huntington's disease [3]. It works by reducing the levels of dopamine, a neurotransmitter involved in movement control [3]. Are there alternatives to tetrabenazine for chorea? Another medication, deutetrabenazine (Austedo), has been approved for treating chorea associated with Huntington's disease [4]. Deutetrabenazine is a deuterium-modified version of tetrabenazine, which may offer a different dosing profile or side effect profile [4]. Where can I find tetrabenazine coupons and savings? Patients seeking to reduce the cost of tetrabenazine may find savings through various programs. Manufacturers often offer patient assistance programs or co-pay cards that can lower out-of-pocket expenses [5]. Online pharmacy discount cards or coupons can also provide savings, though availability and specific discounts may vary [6]. It is advisable to check with the dispensing pharmacy or inquire directly with the drug manufacturer for the most current savings options. How does tetrabenazine work? Tetrabenazine functions as a reversible inhibitor of vesicular monoamine transporter 2 (VMAT2) [3]. By inhibiting VMAT2, it depletes monoamines, including dopamine, in the brain, which helps to alleviate hyperkinetic movements like chorea [3]. What are the side effects of tetrabenazine? Common side effects of tetrabenazine can include drowsiness, fatigue, insomnia, nausea, and parkinsonism [7]. More serious potential side effects involve depression and suicidal ideation, which require careful monitoring by a healthcare provider [7]. Sources: [1] https://www.drugpatentwatch.com/ [2] https://www.drugpatentwatch.com/ [3] https://www.nhs.uk/medicines/tetrabenazine/ [4] https://www.fda.gov/drugs/drug-approvals-and-databases/drug-approval-packages-austedo [5] https://www.astrazeneca.ca/content/az-ca/en_CA/our-focus-areas/neurology/huntingtons-disease.html [6] https://www.goodrx.com/tetrabenazine [7] https://www.drugs.com/xenazine.html
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