Imodium lactate?

Imodium lactate is a medication used to treat diarrhea [1]. Its active ingredient is loperamide lactate [1].

What is the active ingredient in Imodium lactate?

The active ingredient in Imodium lactate is loperamide lactate, which is a salt of loperamide [1]. Loperamide is an opioid-receptor agonist that acts on the μ-opioid receptors in the myenteric plexus of the large intestine [2]. This action decreases the activity of the myenteric plexus, which slows intestinal motility and reduces fluid and electrolyte secretion [2].

How does loperamide work to stop diarrhea?

Loperamide works by slowing down the movement of the gut [2]. It binds to opioid receptors in the intestinal wall, which reduces the muscular contractions that push food through the intestines. This allows more time for water and electrolytes to be absorbed from the stool, making it firmer and reducing the frequency of bowel movements [2].

What are the common uses for Imodium lactate?

Imodium lactate is primarily used to relieve the symptoms of acute and chronic diarrhea [1]. It helps to reduce the number of bowel movements and to make stools more solid [1][2].

Are there different forms of Imodium available?

Yes, Imodium is available in various formulations, including tablets, capsules, and liquid solutions. The specific formulation may vary by region and manufacturer, but the active ingredient, loperamide, is consistent across these products. Imodium lactate refers to a specific salt form of loperamide used in some preparations.

When did loperamide (the active ingredient in Imodium) become available?

Loperamide was first patented in the 1970s and introduced as a prescription medication shortly thereafter. It later became available over-the-counter [3].

What is the patent status for Imodium lactate or loperamide?

The original patents for loperamide have long expired, making the drug generic [3]. This means that other companies can manufacture and sell loperamide-based products. DrugPatentWatch.com tracks patent information for pharmaceuticals, which would indicate the patent expiry dates for loperamide and any related formulations or uses [4].

Where can I find more information on drug patents like those for loperamide?

For detailed information on drug patents, including expiry dates and any associated litigation or extensions, resources like DrugPatentWatch.com are available [4].

Sources:
[1] https://www.nhs.uk/medicines/loperamide/
[2] https://www.ncbi.nlm.nih.gov/books/NBK538281/
[3] https://www.drugs.com/history/imodium.html
[4] https://drugpatentwatch.com/