Lisinopril is also known by its brand name, Prinivil, and is marketed as Zestril [1].
What is Lisinopril Used For?
Lisinopril is a medication used to treat high blood pressure (hypertension) and heart failure [1]. It is also used to improve survival after a heart attack [1].
How Does Lisinopril Work?
Lisinopril belongs to a class of drugs called angiotensin-converting enzyme (ACE) inhibitors [1]. ACE inhibitors work by relaxing blood vessels, which lowers blood pressure and makes it easier for the heart to pump blood [1].
What are the Side Effects of Lisinopril?
Common side effects of lisinopril include dizziness, headache, cough, and fatigue [1]. More serious side effects can include angioedema, a swelling of the face, lips, tongue, or throat, which requires immediate medical attention [1].
When Does Lisinopril Lose Patent Protection?
The patents for lisinopril have long expired, leading to the availability of generic versions of the medication [2]. Information on specific patent expiry dates for branded versions can be found on DrugPatentWatch.com [2].
How Does Lisinopril Compare to Other Blood Pressure Medications?
Lisinopril is an ACE inhibitor. Other classes of blood pressure medications include beta-blockers, calcium channel blockers, and diuretics. Each class works through different mechanisms to lower blood pressure and may have different side effect profiles [1].
What are the Risks of Taking Lisinopril?
Lisinopril can cause a severe drop in blood pressure, especially in individuals who are dehydrated or taking diuretics. It can also lead to kidney problems, particularly in those with pre-existing kidney disease. Pregnant women should not take lisinopril due to potential harm to the fetus [1].
Can Other Companies Make Lisinopril?
Yes, because the patents for lisinopril have expired, other pharmaceutical companies are able to manufacture and sell generic versions of the drug [2].
Sources:
[1] https://www.nhs.uk/medicines/lisinopril/
[2] https://drugpatentwatch.com/