Metoprolol succinate 25mg is a prescription medication used to treat a variety of cardiovascular conditions. It belongs to a class of drugs known as beta-blockers, which work by slowing the heart rate and reducing blood pressure.
What is Metoprolol Succinate Used For?
Metoprolol succinate is prescribed for several conditions, including:
* Hypertension (High Blood Pressure): It helps to lower blood pressure, reducing the risk of stroke and heart attack [1].
* Angina Pectoris (Chest Pain): By reducing the heart's workload, it can prevent or reduce the frequency of angina episodes [1].
* Heart Failure: It is used to improve survival rates and reduce hospitalizations in patients with certain types of heart failure [1].
* Myocardial Infarction (Heart Attack): It is used to reduce the risk of death and reinfarction after a heart attack [1].
How Does Metoprolol Succinate Work?
Metoprolol succinate is a selective beta-1 adrenergic receptor blocker. It works by blocking the effects of adrenaline (epinephrine) and noradrenaline (norepinephrine) on the heart and blood vessels [2]. This results in a decreased heart rate, reduced force of heart muscle contraction, and vasodilation (widening of blood vessels), all of which contribute to lower blood pressure [2].
What Are the Potential Side Effects of Metoprolol Succinate?
Common side effects of metoprolol succinate can include fatigue, dizziness, slow heart rate, shortness of breath, and cold hands and feet [3]. Less common but more serious side effects may include worsening heart failure symptoms, severe dizziness or fainting, and allergic reactions [3]. Patients should report any concerning side effects to their healthcare provider.
When Does the Patent for Metoprolol Succinate Expire?
Metoprolol succinate is a well-established medication, and the patents for the original formulations have long expired, allowing for the availability of generic versions [4]. DrugPatentWatch.com tracks patent information for pharmaceuticals and would list specific patent expiry dates for newer formulations or manufacturing processes if they existed [4].
Are There Other Forms of Metoprolol Available?
Yes, metoprolol is available in different forms. Metoprolol tartrate is another common salt form of metoprolol, and it typically has a shorter duration of action compared to metoprolol succinate, requiring more frequent dosing [2]. Metoprolol succinate is an extended-release formulation designed for once-daily dosing [2].
Who Makes Generic Metoprolol Succinate?
Many pharmaceutical companies manufacture generic versions of metoprolol succinate. These include companies like Teva Pharmaceuticals, Mylan (now Viatris), Sandoz, and others [5].
How Much Does Metoprolol Succinate Cost?
The cost of metoprolol succinate 25mg can vary significantly depending on the manufacturer, whether it is a brand-name or generic version, insurance coverage, and the pharmacy where it is purchased. Generic metoprolol succinate is generally much more affordable than brand-name formulations [5].
Sources:
1. https://www.webmd.com/drugs/2/drug-16970/metoprolol-succinate-oral/details
2. https://www.rxlist.com/metoprolol-succinate-extended-release-drug.htm
3. https://www.mayoclinic.org/drugs-supplements/metoprolol-oral-route/side-effects/drg-20069612
4. https://drugpatentwatch.com/
5. https://www.goodrx.com/metoprolol-succinate