Taking Advil and aspirin together is not recommended without consulting a doctor first. Both Advil and aspirin are nonsteroidal anti-inflammatory drugs (NSAIDs) and can increase the risk of side effects such as stomach bleeding, ulcers, and kidney damage when taken together. The FDA advises that if you need to take both drugs, you should take them at least eight hours apart [2].

Advil is the brand name for ibuprofen, which is commonly used to relieve pain, inflammation, and fever. It works by blocking the production of prostaglandins, which are responsible for causing pain and inflammation [1]. Aspirin, on the other hand, is a salicylate drug that also reduces pain, fever, and inflammation by inhibiting the production of prostaglandins [3].

Both Advil and aspirin have similar effects, but they have different dosages, durations, and side effects. Advil is typically taken every 4-6 hours, while aspirin is taken every 4-8 hours. Advil can cause side effects such as stomach pain, heartburn, and nausea, while aspirin can cause side effects such as ringing in the ears, dizziness, and stomach upset [3].

In conclusion, taking Advil and aspirin together can be risky and is not recommended without consulting a doctor first. Both drugs are NSAIDs and can increase the risk of side effects when taken together. If you need to take both drugs, it is recommended to take them at least eight hours apart. It is important to follow the recommended dosages and to be aware of the potential side effects of each drug [2][3].

Sources:
[1] https://www.drugpatentwatch.com/p/tradename/ADVIL
[2] https://www.fda.gov/drugs/postmarket-drug-safety-information-patients-and-providers/information-about-taking-ibuprofen-and-aspirin-together
[3] https://www.healthline.com/health/pain-relief/aspirin-ibuprofen