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Can i take advil and aspirin together?

See the DrugPatentWatch profile for advil

Combining Advil and Aspirin: A Safe and Effective Combination?

When it comes to managing pain and reducing inflammation, many people turn to over-the-counter (OTC) medications like Advil (ibuprofen) and Aspirin. But can you take them together? The answer is yes, but with some precautions.

Understanding the Risks

While both Advil and Aspirin are nonsteroidal anti-inflammatory drugs (NSAIDs), they work in different ways and have distinct side effect profiles. Advil is a more potent pain reliever and anti-inflammatory agent, whereas Aspirin is primarily used to prevent blood clots and reduce the risk of heart attack and stroke.

Taking Advil and Aspirin together may increase the risk of stomach ulcers, bleeding, and other gastrointestinal side effects. This is because both medications can irritate the stomach lining and reduce the production of protective stomach enzymes.

When to Combine Them

However, there are certain situations where combining Advil and Aspirin may be beneficial. For example:

* If you have a headache and a fever, taking both medications together may provide more effective pain relief and fever reduction.
* If you have a condition like rheumatoid arthritis, taking Advil and Aspirin together may help manage both pain and inflammation.

Precautions and Considerations

Before combining Advil and Aspirin, consider the following:

* Start with a low dose of each medication and gradually increase as needed.
* Monitor your stomach health and report any signs of stomach upset, such as nausea, vomiting, or abdominal pain.
* Avoid taking both medications on an empty stomach, as this may increase the risk of stomach irritation.
* If you have a history of stomach problems, kidney disease, or liver disease, consult your doctor before taking both medications together.

Expert Insights

According to, a leading source for pharmaceutical information, "Combining ibuprofen (Advil) and aspirin may increase the risk of gastrointestinal side effects, including stomach ulcers and bleeding." However, the website also notes that "the risk of serious gastrointestinal side effects is generally low when these medications are used at recommended doses and for short periods of time."


In conclusion, while combining Advil and Aspirin carries some risks, it can be a safe and effective combination when taken responsibly and under the guidance of a healthcare professional. Always follow the recommended dosages, monitor your body's response, and consult your doctor if you have any concerns.


2. Mayo Clinic
3. WebMD
4. American Heart Association


"The risk of serious gastrointestinal side effects is generally low when these medications are used at recommended doses and for short periods of time." -

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